A 55-year-old female is receiving chemotherapy for metastatic carcinoma. She threatens to stop her treatment because of severe nausea and vomiting. The oncologist plans to use prochlorperazine to reduce the nausea and vomiting associated with chemotherapeutic agents. What is the mechanism of action of prochlorperazine?
A. Serotonin 5-HT3 antagonist
B. Blocking dopamine receptors
C. Cannabinoids related
D. Blockage of prostaglandins
E. H2 receptor antagonist
Which of the following NSAIDs is an Enolic acid derivative?
A. Ibuprofen
B. Piroxicam
C. Naproxen
D. Oxaprozin
E. Fenoprofen
A 54-year-old male with a long history of mild persistent asthma on daily fluticasone therapy has been using his albuterol inhaler every day for the past month, and presents requesting a refill. What changes should be made to his current regimen?
A. Add ciclesonide to current regimen
B. Add salmeterol to current regimen
C. Discontinue fluticasone and instead use salmeterol
D. Add cromolyn to current regimen
E. Discontinue fluticasone and add ipratropium to current regimen
LN is 84 YOM who is in hospital for a back surgery. His height is 5 feet and 4 inches, weight 85 kg and NKDA. His past medical history includes hypertension, diabetes mellitus, major depression, hypothyroidism and chronic back pain.
Post-op day 1, LN's medication includes Dexamethasone 8 mg iv q6h with taper dosing, Ondansetron 4 mg iv q6h prn for N/V, Levothyroxine 0.075 mg po daily, Lisinopril 10 mg po daily, Citalopram 20 mg po daily, Docusate sodium / Senna 1 tab po twice a day, Bisacodyl 10 mg suppository daily prn for constipation, Famotidine 20 mg iv q12hr, Metoclopramide 10 mg iv q6h, Metformin 500 mg po bid, D51/2NS with 20 K at 125 mls/hour and Hydromorphone PCA at 0.2 mg/hour of basal rate, demand dose
0.1
mg. lock-out every 6 min, one hour limit 2.2 mg/hour. Pertinent morning labs includes serum creatinine
1.4
mg/dl, Mg 1.5 mg/dl, K 5.0 mmol/L, Na 135 mmol/L.
Which of the following medication may increase LN's Blood glucose?
A. Lisinopril
B. Dexamethasone
C. Famotidine
D. Metoclopramide
E. Hydromorphone
Which of the following class of antidiabetic medications can increase triglycerides?
A. Bile acid sequestrant
B. GLP-1 agonist
C. Thiazolidinediones
D. SGLT2 Inhibitor
E. Alpha-glucosidase inhibitors
The rate that an outcome will occur given a particular exposure, compared to the rate of the outcome occurring in the absence of that exposure is definition of which of the following?
A. Incidence rate
B. Prevelance rate
C. Odds ratio
D. Relative risk
E. Confidence Interval
Number of new cases per population at risk in a given time period is a definition of which of the following?
A. Incidence rate
B. Prevalence rate
C. Mortality rate
D. Odds ratio
E. Confidence Interval
CJ is a 69-year-old male with a history of diabetes, hypertension and hypercholesterolemia. His fasting lipid profile is TC 530 mg/dL; LDL-C 125; HDL-C 48 mg/dL; and TG 640 mg/dL. His A1c 8.1, calculate creatinine clearance is 65mls/hr, BP 135/80 mm Hg, HR 70 beats /min.
His current medications include metformin 1000mg po bid, lisinopril 20mg daily, sitagliptin 50mg bid and atorvastatin 40mg daily.
What is the best pharmacological agent to initiate on CJ?
A. Increase atorvastatin to 80mg
B. Niacin 500mg twice daily
C. Fenofibrate 162mg daily
D. Gemfibrozil 600mg twice daily
E. Fish oil 500mg twice daily
You receive an order for 40mg/kg/dose of Amoxicillin every 12 hours. Pt's weight is 18 lbs. You have 250mg/5ml of amoxicillin suspension.
Calculate the total amount in milliliters needed for 10-day supply. Round up your answer to the nearest 1.
A. 14 mls
B. 132 mls
C. 96 mls
D. 86 mls
E. 36 mls
Which of the following side effects should LT be made aware of while on Divalproex Sodium?
A. Weight gain
B. Oligomenorrhea
C. Alopecia
D. Gynecomastia
E. Gingival hyperplasia
MT is 47-year-old man who presents to the ER with painful, red, swollen area on his left leg. His temperature is 38.4, respiratory rate 30 and heart rate 95. He has been taking cephalexin day 4 today, as prescribed by his primary care physician. His CMP is normal a CBC shows elevated WBC of 16,000/mm3.
What would be the most appropriate antibiotic/s to initiate on MT empirically?
A. Vancomycin IV and Piperacillin/Tazobactam
B. IV Doxycycline and Ceftazidime
C. Nafcillin
D. Vancomycin IV.
E. Ceftriaxone
How many kcal per gram does IV dextrose provide?
A. 0.9 kcal/g
B. 1.2 kcal/g
C. 1.5 kcal/g
D. 3.4 kcal/g
A CD4 count of 180 cells per cubic meter may be evaluated as which of these?
A. Very low
B. Low
C. High
D. Severely high
In the management of acute ischemic stroke, within how many minutes from symptom onset should alteplase be administered?
A. 3 hours
B. 6 hours
C. 12 hours
D. 24 hours
Which H2-receptor blocker may cause gynecomastia in men due to its antiandrogenic effects?
A. Ranitidine
B. Nizatidine
C. Cimetidine
D. Famotidine